Product Information
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产品货号
BD-PA0007
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别名
NR3C4; KD; AIS; SMAX1; HUMARA; AR
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产品名称
Androgen receptor Mouse Monoclonal Antibody
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类别
Antigen Antibody
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基因名称
AR
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Clonality
Monoclonal
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推荐应用
WB,IHC-P,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
367
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免疫原
Purified recombinant fragment of human AR expressed in E. Coli.
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稀释度
WB 1:500-1:2000, IHC-P 1:200-1:1000, ELISA 1:10000
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参考分子量
110kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
2H8
Picture
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Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate. |
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Immunohistochemical analysis of paraffin-embedded human Prostate tissues using Androgen receptor mouse mAb |
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Immunohistochemical analysis of paraffin-embedded human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining. |
Product Details
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
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