Product Information
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产品货号
BD-PA0017
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别名
T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247
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产品名称
CD247 Mouse Monoclonal Antibody
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类别
Antigen Antibody
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基因名称
CD247
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Clonality
Monoclonal
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推荐应用
IHC-P,ICC,FCM,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
919
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免疫原
Purified recombinant fragment of human CD247 expressed in E. Coli.
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稀释度
IHC-P 1:200-1:1000, ICC 1:200-1:1000, FCM 1:200-1:400, ELISA 1:10000
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参考分子量
18kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
4B10
Picture
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Figure3: Immunofluorescence analysis of K562 cells using anti-CD247 mAb (green). Blue: DRAQ5 fluorescent DNA dye. |
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Flow cytometric analysis of Jurkat cells using anti-CD247 mAb (green) and negative control (purple). |
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Immunohistochemical analysis of paraffin-embedded human Thymus tissues using anti-CD247 mouse mAb |
Product Details
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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