Product Information
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产品货号
BD-PA0016
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别名
PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1
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产品名称
PARP Mouse Monoclonal Antibody
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类别
Antigen Antibody
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基因名称
PARP-KLH
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Clonality
Monoclonal
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推荐应用
WB,FCM,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
142
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免疫原
Synthetic peptide of human PARP, conjugated to KLH.
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稀释度
WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
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参考分子量
117kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
7A10
Picture
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Western blot analysis using PARP mouse mAb against Jurkat (1), K562 (2), Hela (3), Raji (4),THP-1 (5) and SW620 (6) cell lysate. |
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Flow cytometric analysis of Jurkat cells using anti-PARP mAb (green) and negative control (purple). |
Product Details
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
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