Product Information
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产品货号
BD-PA0013
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别名
KRT7; cytokeratin 7
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产品名称
CK7 Mouse Monoclonal Antibody
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类别
Antigen Antibody
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基因名称
CK7
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Clonality
Monoclonal
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推荐应用
WB,FCM,Elisa
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反应种属
Human
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存储缓冲液
Ascitic fluid containing 0.03% New type preservative N.
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Human Gene ID
3855
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免疫原
Purified recombinant fragment of human CK7 expressed in E. Coli.
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稀释度
WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
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参考分子量
51kDa
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运输及保存条件
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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宿主
Mouse
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同种型
IgG1
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克隆号
5D12
Picture
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Western blot analysis using CK7 mouse mAb against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate. |
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Flow cytometric analysis of Hela cells using anti-CK7 mAb (green) and negative control (purple). |
Product Details
CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
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