Product Information

• 产品货号 BDAF0011
• 别名 Programmed Cell Death 1 Ligand 2; PD-1 Ligand 2; PD-L2; PDCD1 Ligand 2; Programmed Death Ligand 2; Butyrophilin B7-DC; B7-DC; CD273; PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
• 产品名称 Recombinant Human PD-L2 (N-6His)
• 类别 Diagnostic raw materials
• 推荐应用 Dependent by end user
• 存储缓冲液 Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
• Human Swissprot No. Q9BQ51
• 预测分子量 23.4kDa
• 运输及保存条件 Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
• 表达系统 human cells
• 内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
• 宿主 human cells
• 背景介绍 Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

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